The ReliaQuest Bowl will feature the Vanderbilt Commodores squaring off against the Iowa Hawkeyes on Wednesday, December 31, 2025.

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Vanderbilt vs. Iowa Matchup Info

Game date: Wednesday, December 31, 2025
Game time: 12 p.m. ET
Location: Tampa, Florida
Venue: Raymond James Stadium
TV channel: ESPN

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Vanderbilt vs. Iowa Odds and Prediction

Spread favorite: Commodores (-5.5)
Moneyline: Commodores (-222), Hawkeyes (+182)
Total: 47 points
Pick ATS: Iowa (+5.5)
Pick OU: Over (47)
Prediction: Vanderbilt 27, Iowa 26

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Vanderbilt vs. Iowa Betting Records and Insights

Vanderbilt is 10-2-0 ATS this season.
Iowa has covered eight times in 12 chances against the spread this year.
The Commodores have been favored by 5.5 points or more five times this season, and covered the spread in four of those contests.
The Hawkeyes have been an underdog by 5.5 points or more three times this season, and covered the spread in three of those contests.
Vanderbilt games have gone over the point total eight out of 12 times this season.
Iowa and its opponent have combined to hit the over five out of 12 times this season.