The ReliaQuest Bowl will feature the Vanderbilt Commodores entering a showdown against the Iowa Hawkeyes on Wednesday, December 31, 2025.

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Vanderbilt vs. Iowa Matchup Info

Game date: Wednesday, December 31, 2025
Game time: 12 p.m. ET
Location: Tampa, Florida
Venue: Raymond James Stadium
TV channel: ESPN

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Vanderbilt vs. Iowa Odds and Prediction

Spread favorite: Commodores (-6)
Moneyline: Commodores (-225), Hawkeyes (+185)
Total: 49.5 points
Pick ATS: Iowa (+6)
Pick OU: Over (49.5)
Prediction: Vanderbilt 27, Iowa 26

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Vanderbilt vs. Iowa Betting Records and Insights

Vanderbilt has compiled a 10-2-0 ATS record so far this year.
Iowa has covered eight times in 12 matchups with a spread this year.
The Commodores have an ATS record of 4-1 when playing as at least 6-point favorites this season.
The Hawkeyes have been an underdog by 6 points or more two times this season, and covered the spread both times.
Vanderbilt games have hit the over eight out of 12 times this season.
Iowa games have hit the over five out of 12 times this year.