The Cincinnati Bearcats (3-1) take on a fellow Big 12 foe when they host the No. 14 Iowa State Cyclones (5-0) on Saturday, October 4, 2025 at Nippert Stadium.
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Cincinnati vs. Iowa State Matchup Info
- Game date: Saturday, October 4, 2025
- Game time: 12 p.m. ET
- Location: Cincinnati, Ohio
- Venue: Nippert Stadium
- TV channel: ESPN2
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Cincinnati vs. Iowa State Odds and Prediction
- Spread favorite: Bearcats (-1.5)
- Moneyline: Bearcats (-122), Cyclones (+103)
- Total: 55.5 points
- Pick ATS: Iowa State (+1.5)
- Pick OU: Under (55.5)
- Prediction: Iowa State 25, Cincinnati 24
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Cincinnati vs. Iowa State Betting Records and Insights
- Cincinnati has won three games against the spread this season, while failing to cover once.
- Iowa State has covered three times in five chances against the spread this season.
- The Bearcats have been favored by 1.5 points or more two times this season, and covered the spread in one of those games.
- The Cyclones have won their only game this year when playing as at least 1.5-point underdogs.
- Cincinnati and its opponent have combined to go over the point total three out of four times this season.
- Iowa State games have hit the over twice this year.