Vandy vs. Iowa ReliaQuest Bowl Prediction & Odds

The ReliaQuest Bowl will feature the Vanderbilt Commodores hitting the field against the Iowa Hawkeyes on Wednesday, December 31, 2025.

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Vanderbilt vs. Iowa Matchup Info

  • Game date: Wednesday, December 31, 2025
  • Game time: 12 p.m. ET
  • Location: Tampa, Florida
  • Venue: Raymond James Stadium
  • TV channel: ESPN

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Vanderbilt vs. Iowa Odds and Prediction

  • Spread favorite: Commodores (-5.5)
  • Moneyline: Commodores (-217), Hawkeyes (+178)
  • Total: 47 points
  • Pick ATS: Iowa (+5.5)
  • Pick OU: Over (47)
  • Prediction: Vanderbilt 28, Iowa 27

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Vanderbilt vs. Iowa Betting Records and Insights

  • Vanderbilt has won 10 games against the spread this season, while failing to cover twice.
  • Iowa has compiled an 8-3-1 ATS record so far this year.
  • When playing as at least 5.5-point favorites this season, the Commodores have an ATS record of 4-1.
  • The Hawkeyes have covered the spread when playing as at least 5.5-point underdogs in three of three games this year.
  • Vanderbilt games have gone over the point total eight out of 12 times this season.
  • Iowa and its opponent have combined to hit the over five out of 12 times this year.

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