When the Buffalo Bills square off against the Kansas City Chiefs at 4:25 p.m. ET on Sunday, Nov. 17, our projection system predicts the Bills will take home the win. Our model also projects the spead, point total, and final score, which you can see below.

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Bills vs. Chiefs Game Info and TV Channel

When: Sunday, November 17, 2024 at 4:25 p.m. ET
Where: Highmark Stadium in Orchard Park, New York
TV: CBS
Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)

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Bills vs. Chiefs Odds and Betting Info

Spread favorite: Bills (-2.5)
Moneyline: Bills (-130), Chiefs (+110)
Total: 46 points

Bills vs. Chiefs Prediction

Pick ATS: Bills (-2.5)
Pick OU: Under (46)

Prediction:

Bills 24 - Chiefs 21

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Bills vs. Chiefs Betting Insights

The Bills are 6-4-0 ATS this season.
The Chiefs have compiled a 4-4-1 ATS record so far this season.
Buffalo has an ATS record of 4-2 when playing as at least 2.5-point favorites this season.
Kansas City has been an underdog by 2.5 points or more once this season, and covered the spread.
In the Bills' 10 games this season, the combined scoring has gone over the point total six times.
Chiefs games have gone over the point total four out of nine times this year.

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