The Iowa Hawkeyes (7-4) and the Nebraska Cornhuskers (7-4) play on Friday, November 28, 2025 at Memorial Stadium (Lincoln, NE) in a clash of Big Ten opponents.

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Iowa vs. Nebraska Matchup Info

Game date: Friday, November 28, 2025
Game time: 12 p.m. ET
Location: Lincoln, Nebraska
Venue: Memorial Stadium (Lincoln, NE)
TV channel: CBS
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Iowa vs. Nebraska Odds and Prediction

Spread favorite: Hawkeyes (-6)
Moneyline: Hawkeyes (-228), Cornhuskers (+188)
Total: 39 points
Pick ATS: Iowa (-6)
Pick OU: Over (39)
Prediction: Iowa 27, Nebraska 20

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Iowa vs. Nebraska Betting Records and Insights

Iowa has covered seven times in 11 matchups with a spread this season.
Nebraska has put together a 4-6-1 record against the spread this season.
The Hawkeyes have been favored by 6 points or more four times this season, and covered the spread in two of those matchups.
The Cornhuskers have been an underdog by 6 points or more this year once, and failed to cover the spread.
A total of four out of 11 Iowa games this season have gone over the point total.
So far this year, eight of Nebraska's 11 games with a set number have hit the over.